BDBM60432 BDBM50468001::US11236089, Compound AZD-6738::US8552004, 2.02
SMILES C[C@@H]1COCCN1c1cc(nc(n1)-c1ccnc2[nH]ccc12)C1(CC1)[S@](C)(=N)=O
InChI Key InChIKey=OHUHVTCQTUDPIJ-YBKRRLQSSA-N
Data 17 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 60432
Affinity DataIC50: >2.30E+4nMAssay Description:Inhibition of mTOR in human MDA-MB-468 cells assessed as decrease in AKT phosphorylation at S473 residueMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of mTOR in human MDA-MB-468 cells assessed as decrease in 70S6K S235/236 phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair